Our work bridges micro- and nanobiotechnology, biofabrication, and space life sciences.
Optical Nanomotion Detection (ONMD)
ONMD is a label-free technique that measures nanoscale oscillations of living cells as a signature of metabolic activity.
We develop ONMD-based devices for rapid antimicrobial susceptibility testing (AST/AFST) and adapt them for microgravity and planetary-analogue environments to detect microbial life.
Space Biology and Life Detection
Building on ONMD and AFM, we develop miniaturised life-detection modules for use in space missions and planetary habitats.
These systems aim to sense metabolic nanomotion as a universal indicator of life — independent of specific biochemistry.
Cell Mechanobiology
We study how mechanical forces shape cell behaviour, gene expression, and structural adaptation.
Using microfluidic chips and 3D nanoendoscopy AFM, we quantify cell stiffness, cytoskeletal reorganisation, and nuclear mechanics under shear stress and microgravity.
Biofabrication and Organ-on-Chip Systems
We engineer microenvironments that mimic tissues using soft lithography, 3D printing, and biofabrication.
Our goal is to recreate functional microtissues for mechanobiological studies and antifungal testing under controlled flow conditions
Yeast and Microbial Biotechnology
Yeast serves as a versatile model to study adhesion, flocculation, and stress response.
We explore surface protein mechanics, biofilm formation, and fermentation performance, linking nanoscale properties to industrial applications.
